Faculty

Brian E. Derrick, Ph.D.
Associate Professor of Neurobiology
Office: BSB 3.03.32
Phone: (210) 458-5661
Brian.Derrick@utsa.edu

Ph.D., University of California, Berkeley, 1993.

Research Interests

Behavioral correlates of long-term potentiation, synaptic mechanisms regulating adult neurogenesis, neurocomputation at the dentate-CA3 interface, the contribution of striatal plasticity to drug dependence.

Recent Publications

Sanberg CD, Jones FL, Do VH, Dieguez D Jr, Derrick BE. 5-HT1a receptor antagonists block perforant path-dentate LTP induced in novel, but not familiar, environments. Learn Mem. 2006 Jan-Feb;13(1):52-62.

Kosub KA, Do VH, Derrick BE. NMDA receptor antagonists block heterosynaptic long-term depression (LTD) but not long-term potentiation (LTP) in the CA3 region following lateral perforant path stimulation. Neurosci Lett. 2005 Feb 1;374(1):29-34.

Davis CD, Jones FL, Derrick BE. Novel environments enhance the induction and maintenance of long-term potentiation in the dentate gyrus. J Neurosci. 2004 Jul 21;24(29):6497-506.

Peng H, Derrick BE, Martinez JL Jr. Time-course study of SCG10 mRNA levels associated with LTP induction and maintenance in the rat Schaffer-CA1 pathway in vivo. Brain Res Mol Brain Res. 2004 Jan 5;120(2):182-7.

O'Boyle MP, Do V, Derrick BE, Claiborne BJ. In vivo recordings of long-term potentiation and long-term depression in the dentate gyrus of the neonatal rat. J Neurophysiol. 2004 Feb;91(2):613-22.

Peng H, Derrick BE, Martinez JL Jr. Identification of upregulated SCG10 mRNA expression associated with late-phase long-term potentiation in the rat hippocampal Schaffer-CA1 pathway in vivo. J Neurosci. 2003 Jul 23;23(16):6617-26.

Martinez CO, Do VH, Martinez JL Jr, Derrick BE. Associative long-term potentiation (LTP) among extrinsic afferents of the hippocampal CA3 region in vivo. Brain Res. 2002 Jun 14;940(1-2):86-94.

Do VH, Martinez CO, Martinez JL Jr, Derrick BE. Long-term potentiation in direct perforant path projections to the hippocampal CA3 region in vivo. J Neurophysiol. 2002 Feb;87(2):669-78.

Villarreal DM, Do V, Haddad E, Derrick BE. NMDA receptor antagonists sustain LTP and spatial memory: active processes mediate LTP decay. Nat Neurosci. 2002 Jan;5(1):48-52.

Recent Presentations

University of Chicago, Chicago, IL
"Novel Solutions to the Stability-Plasticity Dilemma in the Hippocampus"
May 7, 2004
Host: Leslie Kay, Ph.D.
Presented by the Committee on Neuroscience speaker series.

Albert Einstein School of Medicine, New York, NY
"Modulation of LTP expression by behavioral state"
May 7, 2003
Host: Illona Vathey, Ph.D.
Presented by the Department of Neuroscience.

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